Research Database

The Diabetes Research Team here at Barts Health / QMUL  have teamed up with the Gastroenterology group for this study. The Principle Investigator (PI) is Professor Qasim Aziz, Professor of Neuro-gastroenterology and co PI is Dr Bobby Huda, Consultant Physician in Diabetes & Metabolism. We are keen to let people who have diabetic gastroparesis know about ongoing research – it is entirely voluntary to take part in this study and you are under no obligation to do so. 

This is a clinical research study to look at the safety and effectiveness of a new investigational medication to help control vomiting and associated symptoms in people with diabetic gastroparesis. The investigational medication will be compared to a placebo (dummy medicine which looks like the study treatment but does not contain any active medicine). Participants in the study will be allocated by chance to which treatment group they go into (randomisation). There is approximately 50% chance of being assigned to receive placebo. 

It is for both men and women aged 18 and over with Type 1 or Type 2 Diabetes With HbA1c range of 11% or lowerAnd diabetic gastroparesis or a 3 month history of symptoms suggestive of gastroparesis with vomiting as a symptomWith no other obstructing lesionWith no parenteral, nasogastric or other enteral tube feeding

There  are other inclusion and exclusion factors which we can go through with you in more detail if you are interested in taking part in the study.

The study will involve 7-8 visits over the course of about 16 weeks. Venue: The Wingate Clinical Trials Unit, Whitechapel, London.  The study treatment will be self-administered as subcutaneous injection twice daily . There may be opportunity to continue for a longer duration on a follow up trial - we do not have the green light for this as yet.

Further information:

Wingate Clinical Trials Unit

Phone: 0207 882 2645

Email: wingateCTU@qmul.ac.uk

MAC study for diabetic gastroparesis

MAC have been conducting clinical research since 1987 and have sites located in Barnsley, Blackpool, Cannock, Leeds, Liverpool, Manchester and Teesside. Working in a variety of different therapy areas including Alzheimer’s, Depression, IBS, Eczema, Migraine and Diabetes to name a few, MAC have a current study for diabetic gastroparesis. The study itself has details on our website here https://www.researchforyou.co.uk/study-3-diabetes(this text approved by wales REC 1) but for ease of access I’ve broken it down here too:

Phase III trial at MAC sites (all) for gastroparesis caused by diabetes16 week study with 7-8 visits to a clinic klStudy medication is known as RelamorelinMAC will reimburse travel expenses or provide them up front for ease of attending clinic visitsPatient payment of £395 for your time and commitment

I have attached two ethically approved posters and leaflets regarding the current diabetes studies that Gastroparesis falls under – no current Gastroparesis specific ones at the moment unfortunately, sorry. If more appropriate, feel free to link to our website and I’d implore any interested patients to have a chat with our patient liaison team on the freephone 0800 9177619, for more info.

Sign up and take part in NHS Research Programmes!

Please take the time to visit the ContactME website and register your details. This is a nationwide project so any UK resident with either, IBS or Intestinal motility disorder can join. By signing up you are not only opening up new pathways for treatment, you are also demonstrating the need for wider studies. 

The process is very simple and you can withdraw your participation at any point. You will be contacted by the research co-ordinator if any relevant research opportunities arise matching your criteria and there is no obligation to take part if you change your mind at a later stage.